منابع مشابه
Vigabatrin versus ACTH in the treatment of infantile spasms.
OBJECTIVE To compare adrenocorticotropic hormone with vigabatrin as a single mono-therapy for infantile spasms. We studied hospitalization time, clinical response, whether complete or partial, time taken for improvement, and presence or absence of recurrence after stopping the medication. Together with improvement of electroencephalographic changes, and time taken for significant response, neur...
متن کاملACTH therapy in infantile spasms: side effects.
162 children with infantile spasms were treated with ACTH at the Children's Hospital, Helsinki, and at the Aurora Hospital, Helsinki, during 1960--76. In a large proportion (37%) of the children the treatment caused pronounced side effects, and the mortality was 4.9%. The most common complications were infections: septic infections, pneumonias, and urinary and gastrointestinal infections. Other...
متن کاملThe use of vigabatrin in infantile spasms in Asian children.
BACKGROUND The use of adrenocorticotrophic hormone (ACTH) and prednisolone in the management of infantile spasms has been well established, but is associated with significant morbidity and cannot be used as long-term medication. Since the introduction of vigabatrin, results have been promising with suggestions currently that it should be used as first-line management of infantile spasms. AIM ...
متن کاملVigabatrin retinal toxicity in children with infantile spasms
OBJECTIVES To determine time to vigabatrin (VGB, Sabril; Lundbeck, Deerfield, IL) induced retinal damage in children with infantile spasms (IS) and to identify risk factors for VGB-induced retinal damage (VGB-RD). METHODS Observational cohort study including 146 participants (68 female, 81 male) with IS, an age-specific epilepsy syndrome of early infancy, treated with VGB. Participants ranged...
متن کاملObservations in Children with Infantile Spasms Treated with Acth
The treatment of children suffering from the type of seizure which is part of the syndrome of infantile spasms has been disappointing since 1841. At this time Dr. W. J. West first described the attacks in his own son and was treating the child with leeches, calomel purgatives, and gum lancing. Though these measures and the others used in the cases later described by Newnham (-1849) may seem biz...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1999
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-13-6-8